Levofloxacin versus clarithromycin in COPD exacerbation: focus on exacerbation-free interval

Levofloxacin versus clarithromycin in COPD exacerbation: focus on exacerbation-free interval.

Antibiotic treatment of bacterial exacerbation of chronic obstructive pulmonary disease (COPD) shows some immediate clinical benefits and may also minimise the frequency of further recurrences. Patients (n=511) were enrolled into a randomised double-blind multicentric study comparing the exacerbation-free interval (EFI), efficacy and safety of 7-day levofloxacin versus 10-day clarithromycin in ...

COPD exacerbation: Lost in translation

The introduction and acceptance of a standard definition for exacerbations of COPD can be helpful in prompt diagnosis and management of these events. The latest GOLD executive committee recognised this necessity and it has now included a definition of exacerbation in the guidelines for COPD which is an important step forward in the management of the disease. This definition is pragmatic and com...

Chlamydia pneumoniae and COPD exacerbation.

Determining prognosis in acute exacerbation of COPD

BACKGROUND Acute exacerbations are the leading causes of hospitalization and mortality in patients with COPD. Prognostic tools for patients with chronic COPD exist, but there are scarce data regarding acute exacerbations. We aimed to identify the prognostic factors of death and readmission after exacerbation of COPD. METHODS This was a retrospective study conducted in the Department of Intern...

Do females behave differently in COPD exacerbation?

INTRODUCTION Little is known about whether there is any sex effect on chronic obstructive lung disease (COPD) exacerbations. This study is intended to describe the possible sex-associated differences in exacerbation profile in COPD patients. METHODS A total of 384 COPD patients who were hospitalized due to exacerbation were evaluated retrospectively for their demographics and previous and cur...